Stem cells and regenerative medicine in sport science.
Stem cells and regenerative medicine in sport science.
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DOI：
10.1042/etls20210014
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发表时间：
2021-10-29
影响因子：
3.8
通讯作者：
Stewart CE
中科院分区：
文献类型：
--
作者：
Stewart CE
在美国，大学体育运动中急性损伤的估计费用为每年15亿美元，不考虑后续康复的费用。除了这种巨大的经济负担，如果没有适当的诊断和相关的干预措施，运动损伤可能会结束一些运动员的职业生涯。随着越来越多的女性参加接触性和旋转式运动，中年人重返体育运动，以及衰老造成的自然伤害都在增加，这种成本和对生活质量的负面影响将扩大。对于那些无法预测和预防的损伤，在运动和临床世界中存在真实的需求，以优化损伤后的修复、恢复和功能。世纪，运动损伤的再生医学竞技场迅速发展，以促进恢复并促进重返运动。这些干预措施利用了与干细胞相关的知识，将其作为损伤修复的潜力。虽然这一领域正在迅速发展，但在开发有效、负担得起的治疗方法时，应考虑干细胞以外的因素，即它们分泌的因子。
The estimated cost of acute injuries in college-level sport in the USA is ∼1.5 billion dollars per year, without taking into account the cost of follow up rehabilitation. In addition to this huge financial burden, without appropriate diagnosis and relevant interventions, sport injuries may be career-ending for some athletes. With a growing number of females participating in contact based and pivoting sports, middle aged individuals returning to sport and natural injuries of ageing all increasing, such costs and negative implications for quality of life will expand. For those injuries, which cannot be predicted and prevented, there is a real need, to optimise repair, recovery and function, post-injury in the sporting and clinical worlds. The 21st century has seen a rapid growth in the arena of regenerative medicine for sporting injuries, in a bid to progress recovery and to facilitate return to sport. Such interventions harness knowledge relating to stem cells as a potential for injury repair. While the field is rapidly growing, consideration beyond the stem cells, to the factors they secrete, should be considered in the development of effective, affordable treatments.