EIS measurements for characterization of muscular tissue by means of equivalent electrical parameters
EIS measurements for characterization of muscular tissue by means of equivalent electrical parameters
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DOI：
10.1016/j.measurement.2014.09.013
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发表时间：
2014-12-01
期刊：
影响因子：
5.6
通讯作者：
Cesarelli, Mario
中科院分区：
文献类型：
--
作者：
Clemente, Fabrizio;Romano, Maria;Cesarelli, Mario
本研究的目的是利用电阻抗频谱(EIS)测量不同状态下肌肉的电学特性。在活体范围内，对32名健康志愿者的前臂屈肌进行了1-60 kHZ的EIS测量。每个受试者都接受了由三个试验组成的方案：静息状态、等长收缩、4分钟放松。测量数据用复非线性最小二乘法用Cole-Cole等效电路进行拟合。结果表明，在所考虑的频率范围内，电流优先流经胞外液，而胞内电阻的分量可以忽略不计。事实上，在回路参数中，R-0.001与稳态的相对变化在收缩过程中和松弛4min后都有非常显著的变化(p<；4min)。(C)2014爱思唯尔有限公司。保留所有权利。
The objective of this work was to study the use of electrical impedance spectroscopy (EIS) measurement to characterize muscle electrical properties in different conditions.In vivo EIS measurements were carried out in the range 1-60 kHz on 32 forearm flexor muscles of healthy volunteers. Each subject underwent to a protocol consisting of three trials: rest condition, isometric contraction, 4 min relaxation. Measured data were fitted with Cole-Cole equivalent electrical circuit using the complex nonlinear least square method. Finally, the relative variations from the steady state of the electrical parameters of the equivalent electrical circuit were estimated.Results obtained are in agreement with the hypothesis that, in the frequency range considered, the current preferentially flows through the extracellular fluid, being the component of intracellular resistance negligible. Among circuital parameters, in fact, the relative variations from steady state of R-0 changed highly significant (p < 0.001) both during contraction and after 4 min relaxation. (C) 2014 Elsevier Ltd. All rights reserved.