Breast cancer risk in Hispanic agricultural workers in California
Breast cancer risk in Hispanic agricultural workers in California
复制标题
DOI：
10.1179/oeh.2005.11.2.123
复制
发表时间：
2005-04-01
影响因子：
--
通讯作者：
Yang, R
中科院分区：
文献类型：
--
作者：
Mills, PK;Yang, R
在一项以加州农场工会成员乳腺癌登记为基础的病例对照研究中，对1988-2001年间新诊断的128例乳腺癌（BC）病例和640例无癌症对照进行了调查。诊断时疾病的分期和分级与加州西班牙裔人群大致相同。乳腺癌的风险与除蘑菇以外的任何特定作物或商品的工作无关，调整后的优势比（or）为6.00 （95% Cl 2.01-18.0）。在控制协变量的情况下，农药使用四分位数中乳腺癌的校正or（和95% ci）分别为1.00、1.30（0.73-2.30）、1.23（0.67-2.27）和1.41（0.66-3.02）。氯丹、马拉硫磷和2,4- d与风险增加有关。在年轻女性、早发性乳腺癌患者和早期诊断的女性（1988-1994）中，使用化学品的风险更大。
In a registry-based case-control study of breast cancer in farm labor union members in California, 128 breast cancer (BC) cases newly diagnosed in 1988-2001 and 640 cancer-free controls were investigated. Stage and grade of disease at diagnosis were about the same as in the California Hispanic population. Risk of breast cancer was not associated with work with any specific crops or commodities except mushrooms, where the adjusted odds ratio (OR) was 6.00 (95% Cl 2.01-18.0). Controlling for covariates, adjusted ORs (and 95% CIs) for breast cancer in quartiles of pesticide use were 1.00, 1.30 (0.73-2.30), 1.23 (0.67-2.27), and 1.41 (0.66-3.02). Chlordane, malathion, and 2,4-D were associated with increased risk. Risk associated with chemical use was stronger in Younger women, those with early-onset breast cancer, and those diagnosed earlier (1988-1994).