Successful aging: Advancing the science of physical independence in older adults.
Successful aging: Advancing the science of physical independence in older adults.
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DOI：
10.1016/j.arr.2015.09.005
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发表时间：
2015-11
影响因子：
13.1
通讯作者：
Pahor M
中科院分区：
文献类型：
--
作者：
Anton SD;Woods AJ;Ashizawa T;Barb D;Buford TW;Carter CS;Clark DJ;Cohen RA;Corbett DB;Cruz-Almeida Y;Dotson V;Ebner N;Efron PA;Fillingim RB;Foster TC;Gundermann DM;Joseph AM;Karabetian C;Leeuwenburgh C;Manini TM;Marsiske M;Mankowski RT;Mutchie HL;Perri MG;Ranka S;Rashidi P;Sandesara B;Scarpace PJ;Sibille KT;Solberg LM;Someya S;Uphold C;Wohlgemuth S;Wu SS;Pahor M
“成功衰老”的概念一直引起科学界的兴趣。尽管有这种长期存在的兴趣，但由于在定义这样一个复杂的、多方面的现象时所涉及的固有挑战，达成一致的定义已被证明是一项艰巨的任务。缺乏一套明确的定义特征来构建成功的衰老，这使得跨研究结果的比较变得困难，并限制了衰老研究的进展。对成功衰老的标志达成共识的领域是身体功能领域。例如，步行速度似乎是整体健康状况的一个很好的替代指标，并预示着身体独立性的维持，这是成功衰老的基石。本文的目的是概述和讨论特定的健康状况、行为因素和生物机制，这些因素标志着活动能力和身体功能的下降，以及有希望的干预措施来对抗这些影响。随着美国和世界各地发达国家的预期寿命持续增加，公共卫生越来越重视所有老年人保持身体独立。
The concept of ‘Successful Aging’ has long intrigued the scientific community. Despite this long-standing interest, a consensus definition has proven to be a difficult task, due to the inherent challenge involved in defining such a complex, multi-dimensional phenomenon. The lack of a clear set of defining characteristics for the construct of successful aging has made comparison of findings across studies difficult and has limited advances in aging research. The domain in which consensus on markers of successful aging is furthest developed is the domain of physical functioning. For example, walking speed appears to be an excellent surrogate marker of overall health and predicts the maintenance of physical independence, a cornerstone of successful aging. The purpose of the present article is to provide an overview and discussion of specific health conditions, behavioral factors, and biological mechanisms that mark declining mobility and physical function and promising interventions to counter these effects. With life expectancy continuing to increase in the United States and developed countries throughout the world, there is an increasing public health focus on the maintenance of physical independence among all older adults.