THE NUCLEOTIDE-SEQUENCE OF RAT ALPHA-TUBULIN - 3'-END CHARACTERISTICS, AND EVOLUTIONARY CONSERVATION
THE NUCLEOTIDE-SEQUENCE OF RAT ALPHA-TUBULIN - 3'-END CHARACTERISTICS, AND EVOLUTIONARY CONSERVATION
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DOI：
10.1093/nar/9.12.2691
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发表时间：
1981-01-01
影响因子：
14.9
通讯作者：
LITTAUER, UZ
中科院分区：
文献类型：
--
作者：
GINZBURG, I;BEHAR, L;LITTAUER, UZ
本文描述了大鼠α-微管蛋白cDNA克隆的结构和序列。编码区的3 '端含有C-末端酪氨酸的密码子，其先前被认为是后修饰添加到完整的多肽链上。当比较大鼠和鸡的α-微管蛋白时，观察到编码序列的高度同源性，而3 '-非翻译区有相当大的差异。
The structure and sequence of rat α-tubulin cDNA clone is being described. The 3'-end of the coding region contains the codon for a C-terminal tyrosine, which was previously considered to be post-translationally added to the completed polypeptide chain. A close homology in the coding sequence is observed when α-tubulin from rat and chick are compared, while the 3'-non-translated region has diverged considerably.