Endothelium removal augments vasodilation by sodium nitroprusside and sodium nitrite.
Endothelium removal augments vasodilation by sodium nitroprusside and sodium nitrite.
复制标题
内皮去除增强硝普钠和亚硝酸钠的血管舒张作用。
DOI：
10.1016/0014-2999(85)90527-8
复制
发表时间：
1985
影响因子：
5
通讯作者：
Che Su
中科院分区：
文献类型：
--
作者：
YasufumiShirasaki;Che Su
Sodium nitroprusside (3–100 nM) and sodium nitrite (0.03–1 mM) caused relaxation of the rat aortic ring segments precontracted by norepinephrine. The relaxation wassignificantly augmented by removal of endothelium, and this augmentation was greater in the aorta from spotaneoously hypertensive rats (SHR) than Wistar Kyoto rats (WKY). The mechanismsremains unknown but such augmentation may be clinically favorable to the use of nitrovasodilators.
