Interactomics in the human intestine -: Lactobacilli and Bifidobacteria make a difference
Interactomics in the human intestine -: Lactobacilli and Bifidobacteria make a difference
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DOI：
10.1097/mcg.0b013e31817dbd62
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发表时间：
2008-09-01
影响因子：
2.9
通讯作者：
de Vos, Willem M.
中科院分区：
文献类型：
--
作者：
Boesten, Rolf J.;de Vos, Willem M.
支持肠道微生物群与健康状况之间相关性的科学证据引起了人们对微生物-宿主相互作用研究的极大兴趣。它产生了从分析病原体到分析共生菌和益生菌的范式转变。本文综述了近年来基于组学研究的乳酸菌和双歧杆菌相互作用机制。这一信息有望为进一步揭示包括微生物和宿主细胞相互作用组在内的一系列相互作用提供新的途径。
Scientific evidence that supports a correlation between our intestinal microbiota and health status has caused significant interest in microbe-host interaction studies. It has generated a paradigm shift from analyzing pathogens to that involving commensal and probiotic bacteria. This review summarizes the interaction mechanisms described for Lactobacilli and Bifidobacteria based on recent omics-based developments. This information is expected to provide new avenues for further unravelling the set of interactions that includes the interactome of microbial and host cells.