2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium
2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium
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DOI：
10.1111/trf.13250
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发表时间：
2015-09-01
期刊：
影响因子：
2.9
通讯作者：
Glynn, Simone
中科院分区：
文献类型：
--
作者：
Spitalnik, Steven L.;Triulzi, Darrell;Glynn, Simone
2015年3月25日和26日，美国国家心脏、肺和血液研究所在位于马里兰州贝塞斯达的美国国立卫生研究院（NIH）校园内主办了一次关于输血医学科学现状的会议，330名注册者参加了会议。会议的目标是确定在未来5到10年内可以回答的重要研究问题，这些问题将有可能改变输血医学的临床实践。这些问题可以通过基础、转化和/或临床研究来解决，并集中在四个领域：三种“经典”输血产品（即，红细胞、血小板和血浆）和献血者问题。会前，四个工作组（每个领域一个工作组）准备了五个主要问题供讨论，沿着了五至十个其他问题供审议。在会议本身，所有这些问题，以及其他问题，都在主题演讲，小组分组会议和大组会议中进行了讨论，所有与会者都参与了公开讨论。除了本文提供的最终问题清单外，会议与会者还确定了多个跨领域的总体主题，这些主题解决了所有四个领域的共同问题;还提供了后者。预计解决这些科学优先事项，并仔细关注总体主题，将为NIH制定的资金优先事项提供信息，并为改变未来的输血医学实践提供坚实的研究平台。
On March 25 and 26, 2015, the National Heart, Lung, and Blood Institute sponsored a meeting on the State of the Science in Transfusion Medicine on the National Institutes of Health (NIH) campus in Bethesda, Maryland, which was attended by a diverse group of 330 registrants. The meeting's goal was to identify important research questions that could be answered in the next 5 to 10 years and which would have the potential to transform the clinical practice of transfusion medicine. These questions could be addressed by basic, translational, and/or clinical research studies and were focused on four areas: the three "classical" transfusion products (i.e., red blood cells, platelets, and plasma) and blood donor issues. Before the meeting, four working groups, one for each area, prepared five major questions for discussion along with a list of five to 10 additional questions for consideration. At the meeting itself, all of these questions, and others, were discussed in keynote lectures, small-group breakout sessions, and large-group sessions with open discourse involving all meeting attendees. In addition to the final lists of questions, provided herein, the meeting attendees identified multiple overarching, cross-cutting themes that addressed issues common to all four areas; the latter are also provided. It is anticipated that addressing these scientific priorities, with careful attention to the overarching themes, will inform funding priorities developed by the NIH and provide a solid research platform for transforming the future practice of transfusion medicine.