Hormonal correlates of 'masculinization' in female spotted hyaenas (Crocuta crocuta). 1. Infancy to sexual maturity.
Hormonal correlates of 'masculinization' in female spotted hyaenas (Crocuta crocuta). 1. Infancy to sexual maturity.
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雌性斑鬣狗（Crocuta crocuta）“雄性化”的激素相关性。
DOI：
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Paul Licht
中科院分区：
文献类型：
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作者：
S. Glickman;Laurence G. Frank;S. Pavgi;Paul Licht
这份报告涉及高度“男性化”的雌性哺乳动物——斑点鬣狗（Crocuta crocuta）性成熟时的激素浓度。对 12 只雌性和 8 只 2.5-62.5 个月大的雄性鬣狗进行的纵向研究中，通过放射免疫测定法测定了睾酮、雄烯二酮和雌激素的血浆浓度。 26.5 个月大后，男性的睾酮浓度显着高于女性，但早期的测量结果在性别之间没有差异。成年雌性鬣狗的平均睾酮浓度（0.4-0.5 ng ml-1）与其他几种不表现出“雄性”特征的雌性哺乳动物相似，但在大多数年龄段，雌性鬣狗的雄烯二酮平均浓度（2.5-5.5 ng ml-1）显着高于雄性（1.0-2.0 ng ml-1）。雌性直到大约 14 个月大时才检测到雌激素（低于 0.03 ng ml-1），然后在 18 至 30 个月之间增加（至大约 0.13 ng ml-1）；男性体内的雌激素仍然检测不到。女性雌激素的增加与乳头增大以及泌尿生殖道的大小和弹性的变化相对应，从而允许通过阴蒂进行交配和分娩。 4-7 个月时的性腺切除术（两名男性和四名女性）导致睾酮和雌激素浓度检测不到，并且雄烯二酮显着减弱（至约 0.39 ng ml-1），表明性腺是这三种类固醇的主要来源。性腺切除术还消除了体重、乳头发育和泌尿生殖道弹性方面的性别差异。
This report is concerned with hormone concentrations accompanying sexual maturation in a highly 'masculinized' female mammal, the spotted hyaena, Crocuta crocuta. Plasma concentrations of testosterone, androstenedione and oestrogen were determined by radioimmunoassay in a longitudinal study of 12 female and eight male hyaenas 2.5-62.5 months old. Concentrations of testosterone were significantly higher in males than in females after 26.5 months of age, but earlier measurements did not differ between sexes. Mean testosterone concentrations in adult female hyaenas (0.4-0.5 ng ml-1) were similar to those in several other female mammals that do not display a 'masculine' profile, but mean concentrations of androstenedione (2.5-5.5 ng ml-1) in female hyaenas were significantly higher than in males (1.0-2.0 ng ml-1), at most ages. Oestrogen could not be detected (less than 0.03 ng ml-1) in females until about 14 months of age and then increased (to approximately 0.13 ng ml-1) between 18 and 30 months; oestrogen remained undetectable in males. This rise in oestrogen in females corresponded to nipple enlargement and to changes in the size and elasticity of the urogenital meatus, permitting copulation and parturition through the clitoris. Gonadectomy (two males and four females) at 4-7 months resulted in nondetectable concentrations of testosterone and oestrogen and a marked attenuation in androstenedione (to approximately 0.39 ng ml-1), indicating that the gonads are the major source of these three steroids. Gonadectomy also eliminated sex differences in weight, nipple development and elasticity of the urogenital meatus.
雌性斑鬣狗（Crocuta crocuta）“雄性化”的激素相关性。
DOI：
10.1530/jrf.0.0950463
发表时间：
1992
期刊：
Journal of reproduction and fertility
影响因子：
--
作者：
Licht,P;Frank,LG;Pavgi,S;Yalcinkaya,TM;Siiteri,PK;Glickman,SE
通讯作者：
Glickman,SE
金披地松鼠（Spermophilus Lateris）血浆睾酮和黄体生成素水平的周期性节律。
影响因子：
3.6
作者：
Licht,P;Zucker,I;Hubbard,G;Boshes,M
通讯作者：
Boshes,M