Abdominal fat distribution in pre- and postmenopausal women: The impact of physical activity, age, and menopausal status
Abdominal fat distribution in pre- and postmenopausal women: The impact of physical activity, age, and menopausal status
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DOI：
10.1053/meta.2001.24931
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发表时间：
2001-08-01
影响因子：
9.8
通讯作者：
Weinstock, RS
中科院分区：
文献类型：
--
作者：
Kanaley, JA;Sames, C;Weinstock, RS
总体脂与年龄相关的增加已有报道，但绝经对腹部脂肪分布的影响仍不清楚。本研究的目的是利用磁共振成像(MRI)来确定绝经状态对腹部脂肪分布的影响。此外，我们还研究了腹部脂肪分布对血脂和瘦素浓度的影响。对接受雌激素替代治疗(ERT)的23名绝经前(前)、27名绝经后(后)和28名绝经后妇女进行了腹部局部脂肪、血脂和血清瘦素浓度的测量。这些女性在体重指数(BMI)和全身脂肪质量方面进行了匹配。年龄和绝经状况对总腹部脂肪、内脏脂肪和皮下脂肪没有显著的预测作用，而体力活动是显著的预测因素(P
Age-related increases in total body fat have been reported, but the impact of menopause on abdominal fat distribution is still unclear. The purpose of this study was to determine the impact of menopausal status on abdominal fat distribution using magnetic resonance imaging (MRI). In addition, we investigated the influence of abdominal fat distribution on blood lipid profiles and leptin concentrations. Twenty-three premenopausal (PRE), 27 postmenopausal (POST), and 28 postmenopausal women on estrogen replacement therapy (ERT) had measurements of regional abdominal fat, blood lipids, and serum leptin concentrations. The women were matched for body mass index (BMI) and total body fat mass. Age and menopausal status were not found to be significant predictors of total abdominal fat, visceral fat, or subcutaneous fat, while physical activity was a significant predictor (P