TOWARDS AN IMPROVED LIPID-LOWERING DIET: ADDITIVE EFFECTS OF CHANGES IN NUTRIENT INTAKE

TOWARDS AN IMPROVED LIPID-LOWERING DIET: ADDITIVE EFFECTS OF CHANGES IN NUTRIENT INTAKE
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改善降脂饮食:营养摄入变化的累加效应

DOI:
10.1016/s0140-6736(81)91339-8
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发表时间:
1981
期刊:
The Lancet
影响因子:
--
通讯作者:
A. Swan
A. Swan
中科院分区:
--
文献类型:
--
作者:
B. Lewis;M. Katan;I. Merkx;N. Miller;F. Hammett;R. Kay;A. Nobels;A. Swan

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To identify diets that are more effective than existing ones in reducing lipoproteinmediated risk of atherosclerotic heart disease, the serum lipid and lipoprotein response to three modified diets was studied in twelve normal men living in an institution. The "Western" reference diet (40% energy from fat, P/S ratio 0.27) was compared in Latin square design with a fat-modified diet (diet B, 27% energy from fat, P/S 1·0, reduced cholesterol content); with a fat-modified diet supplemented with fruit, vegetable, and cereal fibre (diet C); and with a diet providing 40% energy from fat, having P/S ratio 1.0 and supplemented by fibre (diet D). The effects of fat modification and fibre-supplementation (diets C and D) were strongly additive—a fall in serum cholesterol by 24-29%, in low-density-lipoprotein (LDL) cholesterol by 31-34%, and in serum triglyceride by 21-26%; and the reduction, by diet C, of the ratio of serum cholesterol to high-densitylipoprotein (HDL)-cholesterol by 21%, and that of LDL-cholesterol to HDL2-cholesterol by 26%. The additive effects of multiple changes in nutrient intake, each moderate in extent, permits the design of diets which are remarkably effective in reducing serum-cholesterol level.
DOI: --
发表时间: 1980
期刊: The American journal of pathology
影响因子: --
作者:
Wagner,WD;StClair,RW;Clarkson,TB;Connor,JR
通讯作者: Connor,JR
营养与癌症——关于结肠癌、乳腺癌、前列腺癌和胃癌病因的机制。
DOI: --
发表时间: 1980
期刊: Bulletin of the New York Academy of Medicine
影响因子: --
作者:
Weisburger,JH;Reddy,BS;Hill,P;Cohen,LA;Wynder,EL;Spingarn,NE
通讯作者: Spingarn,NE