Activation of basal forebrain cholinergic neurons differentially regulates brain-derived neurotrophic factor mRNA expression in different projection areas.
Activation of basal forebrain cholinergic neurons differentially regulates brain-derived neurotrophic factor mRNA expression in different projection areas.
复制标题
基底前脑胆碱能神经元的激活差异调节不同投影区域的脑源性神经营养因子 mRNA 表达。
DOI：
10.1016/0304-3940(92)90049-d
复制
发表时间：
1992
影响因子：
2.5
通讯作者：
Persson,H
中科院分区：
文献类型：
--
作者：
Boatell,LL;Lindefors,N;Ballarin,M;Ernfors,P;Mahy,N;Persson,H
Afferent cholinergic pathways from the basal forebrain were activated by injections of the glutamate analog quisqualate either into the nucleus basalis or into the medial septal nucleus. Nucleus basalis injections had no effect on the expression of brain-derived neurotrophic factor (BDNF) mRNA in its neocortical projection areas as measured by in situ hybridization. In contrast, 7 h after an injection into the septum the level of BDNF mRNA increased 3- to 5-fold in the dentate gyrus, throughout CA1 to CA3 in the hippocampus and in the piriform cortex.
