Stability on Drying of Cyclodextrin Precipitates of Volatile Nonelectrolytes.
Stability on Drying of Cyclodextrin Precipitates of Volatile Nonelectrolytes.
复制标题
挥发性非电解质环糊精沉淀的干燥稳定性。
DOI：
10.1246/bcsj.67.2744
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发表时间：
1994
影响因子：
4
通讯作者：
T. Deguchi
中科院分区：
文献类型：
--
作者：
I. Sanemasa;Yue Wu;Yuuki Koide;T. Fujii;Hiroko Takahashi;T. Deguchi
环糊精（CyD’s）作为包合物与22种挥发性非电解质（客体）在25°C的水溶液中沉淀。在制备和干燥后立即测量沉淀的guest/CyD摩尔比。在50°C的减压条件下，使用吸水泵将沉淀物干燥5小时，得到的guest/CyD摩尔比与在五氧化二磷干燥器中干燥并在干燥器中储存两周所得到的相同。碘-α-CyD配合物在干燥时非常稳定，旁边是1,2,3-三甲苯-α-CyD和1,2,4-三甲苯-β-CyD配合物；其他的客cyd复合物或多或少是不稳定的。稳定性与最大驻留在CyD腔内的客体分子的范德华体积大致相关。
Cyclodextrins (CyD’s) were precipitated in aqueous medium at 25 °C as inclusion complexes with twenty-two volatile nonelectrolytes (guests). The guest/CyD molar ratios of precipitates were measured immediately after preparation and after drying. Drying the precipitates for five hours at 50 °C under reduced pressure using a water-suction pump gave the same guest/CyD molar ratios as those obtained by drying in a desiccator over diphosphorus pentaoxide and stored there for two weeks. An iodine–α-CyD complex is quite stable on drying and, next to it are 1,2,3-trimethylbenzene–α-CyD and 1,2,4-trimethylbenzene–β-CyD complexes; other guest–CyD complexes are more or less unstable. The stability was found to be roughly correlated to the van der Waals volume of guest molecule(s) resident maximally in the CyD cavity.