Detecting viruses by using salivary diagnostics.
Detecting viruses by using salivary diagnostics.
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通过使用唾液诊断来检测病毒。
DOI：
10.14219/jada.archive.2012.0338
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发表时间：
2012-10
期刊：
影响因子：
--
通讯作者：
Malamud D
中科院分区：
文献类型：
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作者：
Corstjens PL;Abrams WR;Malamud D
近年来，涉及使用口腔流体的诊断已经变得越来越商业化，并且由于其相对容易使用、低成本和无创收集口腔流体用于测试而受到特别关注。作者讨论了使用唾液诊断进行病毒检测，重点是通过使用即时设备快速检测感染。特别是，他们审查了人类免疫缺陷病毒，丙型肝炎病毒和人乳头瘤病毒的唾液诊断。口腔粘膜渗出液含有分泌性免疫球蛋白（IG）A以及IgM和IgG，这使其成为基于免疫诊断的装置的良好来源。由于患者经常比医生更经常地去看牙医，因此牙科社区越来越多地讨论从业者需要了解唾液诊断，并愿意和能够对患者进行这些测试。
Diagnostics that involve the use of oral fluids have become increasingly available commercially in recent years and are of particular interest because of their relative ease of use, low cost and noninvasive collection of oral fluid for testing. The authors discuss the use of salivary diagnostics for virus detection with an emphasis on rapid detection of infection by using point-of-care devices. In particular, they review salivary diagnostics for human immunodeficiency virus, hepatitis C virus and human papillomavirus. Oral mucosal transudate contains secretory immunoglobulin (Ig) A, as well as IgM and IgG, which makes it a good source for immunodiagnostic-based devices. Because patients often visit a dentist more regularly than they do a physician, there is increased discussion in the dental community regarding the need for practitioners to be aware of salivary diagnostics and to be willing and able to administer these tests to their patients.