Metastasizing Eccrine Porocarcinoma Of The Nose: Case-Report With Immunohistochemical Study And Review Of The Literature
Metastasizing Eccrine Porocarcinoma Of The Nose: Case-Report With Immunohistochemical Study And Review Of The Literature
复制标题
DOI：
10.5580/2276
复制
发表时间：
2007-12
期刊：
影响因子：
--
通讯作者：
E. Ferri;G. Iaderosa;E. Armato
中科院分区：
文献类型：
--
作者：
E. Ferri;G. Iaderosa;E. Armato
汗腺小汗腺癌是一种罕见的汗腺恶性肿瘤。它主要影响老年人。临床诊断很困难，病变经常被误认为鳞状细胞癌。大多数EP发生在下肢的底部，但也可以在手掌、躯干和上肢发现。文献中报道了29例发生在头颈部，仅4例累及鼻部。大多数EP与局部侵袭性疾病和预后较差的远处转移率不同有关。免疫组织化学和广泛手术切除是早期诊断的基础。没有数据支持辅助治疗的使用。本文报告1例心脏移植受者鼻锥体EP转移至股骨的病例，强调鉴别诊断、治疗方法及预后不良的问题。
Eccrine Porocarcinoma (EP) is a rare malignancy of eccrine sweat gland. It mostly affects old people. Clinical diagnosis is difficult and lesions are often mistakenly identified as squamous cell carcinoma. The majority of EPs occur on the soles of the lower extremities, but can also be found on palms, trunk, upper extremities. In the Literature twenty-nine cases have been reported in the head and neck region and only four cases involve the nose. The majority of EPs were associated with locally aggressive disease and a poor outcome with a variable rate of distant metastasis. Early diagnosis with immunohistochemistry and wide surgical excision are basic. There are no data to support the use of adjuvant therapy. A case of EP of the nasal pyramid in a cardiac transplant recipient metastasizing to femural bone is presented to emphasize the problems in the differential diagnosis, the treatment's modalities and the poor prognosis.