Peptide ligation using a building block having a cysteinyl prolyl ester (CPE) autoactivating unit at the carboxy terminus
Peptide ligation using a building block having a cysteinyl prolyl ester (CPE) autoactivating unit at the carboxy terminus
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DOI：
10.1246/cl.2007.76
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发表时间：
2007-01-05
影响因子：
1.6
通讯作者：
Aimoto, Saburo
中科院分区：
文献类型：
--
作者：
Kawakami, Toru;Aimoto, Saburo
描述了使用含有半胱氨酰脯氨酸酯(CPE)自激活单元的积木连接CPE多肽。该多肽构建块可通过标准的Fmoc化学方法制备，并用于硫醇介导的连接，如天然化学连接。
CPE peptide ligation using a building block containing a cysteinyl prolyl ester (CPE) autoactivating unit is described. The peptide building block can be prepared by a standard Fmoc chemistry and used in thiol-mediated ligation, such as native chemical ligation.