B-type natriuretic peptide as an independent correlate of nocturnal voiding in Japanese women

B-type natriuretic peptide as an independent correlate of nocturnal voiding in Japanese women
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DOI:
10.1002/nau.22250
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发表时间:
2012-11-01
影响因子:
2
通讯作者:
Ogawa, Osamu
Ogawa, Osamu
中科院分区:
医学3区
文献类型:
--
作者:
Yoshimura, Koji;Nakayama, Takeo;Ogawa, Osamu

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目的探讨客观心血管参数是否与女性夜间排尿独立相关。方法对5,980名妇女进行问卷调查,并结合人体测量、生理生化等指标进行分析。通过国际前列腺症状评分和膀胱过度活动症症状评分评估夜间排尿。我们测量的变量包括先前报道的夜间排尿相关因素,如年龄、高血压史和糖尿病史,以及关注心血管功能的变量,如心踝血管指数、增强指数、踝臂指数、血浆B型利钠肽(BNP)和C反应蛋白(CRP)。结果年龄[比值比(OR):1.058,P?
Aims To investigate whether objective cardiovascular parameters have an independent association with nocturnal voiding in women. Methods Thirty-two parameters derived from questionnaires, and anthropometric, physiological and biochemical measures of 5,980 women were applied for analysis. Nocturnal voiding was assessed by the International Prostate Symptom Score and the Overactive Bladder Symptom Score. We measured variables including previously reported correlates of nocturnal voiding, such as age, a history of hypertension, and a history of diabetes, as well as those focusing on cardiovascular function, such as the cardio-ankle vascular index, the augmentation index, the ankle-brachial index, plasma B-type natriuretic peptide (BNP), and C-reactive protein (CRP). Results Age [odds ratio (OR): 1.058, P?