Metabolites of L-(35S)cysteine Injected into the Peritoneal Cavity of Rainbow Trout.
Metabolites of L-(35S)cysteine Injected into the Peritoneal Cavity of Rainbow Trout.
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L-(35S)半胱氨酸的代谢物注射到虹鳟鱼的腹膜腔中。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
M. Sakaguchi
中科院分区：
文献类型：
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作者：
M. Yokoyama;M. Kaneniwa;M. Sakaguchi
为了阐明虹鳟鱼体内半胱氨酸转化为牛磺酸的途径，将放射性L-半胱氨酸注入虹鳟鱼腹腔，并追踪其后续代谢产物。放射性半胱氨酸衍生的代谢产物的分布进行了检查，在整个鱼体和排泄物。牛磺酸，亚牛磺酸，硫酸盐被认为是主要的代谢产物中的酸溶性部分的鱼体。在注射放射性L-半胱氨酸后的前24小时内，大量这些代谢产物被排泄。这些发现表明，鱼体内的半胱氨酸代谢迅速。虹鳟鱼产生的硫酸盐量约为牛磺酸加亚牛磺酸的一半。由硫酸盐的形成所证明，推测虹鳟鱼中存在通过半胱氨酸亚磺酸盐的代谢途径。
To clarify the pathway from cysteine to taurine in rainbow trout, radioactive L-cysteine was inject ed into the peritoneal cavity of fish and its subsequent metabolites were traced. The distribution of metabolites derived from radioactive cysteine was examined in the whole fish body and in the excreta. Taurine, hypotaurine, and sulfate were found to be major metabolites in the acid-soluble fraction of the fish body. A large amount of these metabolites was excreted within the first 24 h after the injection of radioactive L-cysteine. These findings indicate that cysteine in the fish body is metabolized rapidly. The amount of sulfate produced in rainbow trout was about one half that of taurine plus hypotaurine. As evidenced by the formation of sulfate, presumably there is a metabolic pathway through cysteine sulfinate in rainbow trout.
动物肝脏和大脑中半胱氨酸亚磺酸脱羧酶活性和牛磺酸浓度的物种、年龄和性别比较。
DOI：
10.1016/0305-0491(85)90232-9
发表时间：
1985
期刊：
Comparative biochemistry and physiology. B, Comparative biochemistry
影响因子：
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作者：
Worden,JA;Stipanuk,MH
通讯作者：
Stipanuk,MH
DOI：
10.1016/s0021-9258(18)33025-4
发表时间：
1983-02
期刊：
The Journal of biological chemistry
影响因子：
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作者：
O. Griffith
通讯作者：
O. Griffith