Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green
Intraoperative evaluation of skin-flap viability using laser-induced fluorescence of indocyanine green
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DOI：
10.1054/bjps.2002.3969
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发表时间：
2002-12-01
期刊：
影响因子：
--
通讯作者：
Mühlbauer, W
中科院分区：
文献类型：
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作者：
Holm, C;Mayr, M;Mühlbauer, W
激光诱导吲哚菁绿荧光（ICG）是一种评价皮肤灌注的新方法，它优于传统的荧光素血管造影。在一项前瞻性临床研究中，应用ICG荧光血管成像技术评估术中皮瓣灌注情况。术后1周比较ICG成像结果与临床结果。术中ICG填充缺损总是与伤口愈合延迟有关。在50%的患者中，脱落和上皮溶解的区域与染料填充缺陷的区域准确对应。无ICG缺损的皮瓣均基本愈合。这些结果表明，ICG荧光是评估有或无轴向血管的带蒂皮瓣营养血流的敏感工具。未来的临床研究需要建立与术后过程中皮肤活力相关的临界阈值荧光指数。(C) 2002年英国整形外科医师协会。Elsevier Science Ltd.出版。版权所有。
Laser-induced fluorescence of indocyanine green (ICG) is a new method for evaluating skin perfusion, which is superior to conventional fluorescein angiography. In a prospective clinical study ICG fluorescence video-angiography was used for the intraoperative evaluation of skin-flap perfusion. The results of ICG imaging were compared with clinical outcome 1 week postoperatively. Intraoperative ICG filling defects were always associated with delayed wound healing. In 50% of the patients, the regions of sloughing and epitheliolysis corresponded accurately to the regions of dye-filling deficits. All of the flaps without ICG filling defects healed primarily. These results suggest that ICG fluorescence is a sensitive tool for assessing nutritive blood flow in pedicled skin flaps with and without an axial vessel. Future clinical studies are required to establish critical threshold fluorescence indices that correlate with skin viability in the postoperative course. (C) 2002 The British Association of Plastic Surgeons. Published by Elsevier Science Ltd. All rights reserved.