Formamidobisabolene-based derivatives from a sponge Axinyssa sp.
Formamidobisabolene-based derivatives from a sponge Axinyssa sp.
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来自海绵 Axinyssa sp 的甲酰胺双没药烯衍生物。
DOI：
10.1016/j.tet.2014.04.008
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发表时间：
2014-06-03
期刊：
影响因子：
2.1
通讯作者：
Lin, Wenhan
中科院分区：
文献类型：
--
作者：
Cheng, Wei;Liu, Dong;Lin, Wenhan
Chemical examination of a Chinese sponge Axinyssa sp. resulted in the isolation of 12 new formamidobisabolene-based analogues named axinyssines A-L (1-12), along with a new natural product (13) and three known formamidobisabolenes (14-16). Their structures were determined on the basis of extensive NMR and mass spectroscopic analyses in association with ICD data, Mosher reaction and chemical conversion for the assignment of absolute configurations. All compounds were evaluated for antitumor and antimicrobial activities. (C) 2014 Elsevier Ltd. All rights reserved.
