Respiratory distress syndrome in twin infants compared with singletons
Respiratory distress syndrome in twin infants compared with singletons
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DOI：
10.1016/j.ajog.2003.11.020
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发表时间：
2004-07-01
影响因子：
9.8
通讯作者：
Hallman, M
中科院分区：
文献类型：
--
作者：
Marttila, R;Kaprio, J;Hallman, M
目的：本研究的目的是确定胎龄特异性呼吸窘迫综合征（RDS）的发病率和危险因素，双胞胎与singletons.Study设计：850,406单胞胎和23,278双胞胎婴儿出生在芬兰1987年和2000年之间活着进行了分析。一些产前和围产期/intratal factors进行了evaluated.Results：在小于28周的妊娠，RDS的发病率较高，在第一和第二个出生的双胞胎相比，单胎。在妊娠晚期，第一胎双胞胎的RDS发生率明显低于其他双胞胎。同性别和异性双胞胎之间RDS的一致性没有差异。阴道分娩，女性，第一次出生，并被保护从RDS的双胞胎中较轻的。结论：考虑到妊娠后，双胞胎是不是在RDS的风险较高的单胎相比，除了在非常早期的妊娠。环境因素在双胞胎RDS的易感性中占主导地位。(C)2004年爱思唯尔公司All rights reserved.
Objective: The purpose of this study was to determine gestational age-specific incidence and risk factors of respiratory distress syndrome (RDS) in twins compared with singletons.Study design: An analysis of 850,406 singleton and 23,278 twin infants born alive in Finland between 1987 and 2000 was performed. A number of antenatal and perinatal/intranatal factors were evaluated.Results: At less than 28 weeks of gestation, the incidence of RDS was higher in both first- and second-born twins compared with singletons. At more advanced gestation, first-born twins had a significantly lower incidence of RDS compared with the others. There was no difference in the concordance of RDS between same-sex and opposite-sex twin pairs. Vaginal delivery, female sex, being born first, and being the lighter of the twins protected from RDS.Conclusion: After taking into account gestation, twins are not at higher risk of RDS compared with singletons except at very early gestation. Environmental factors predominate over genetic ones in the predisposition to RDS in twins. (C) 2004 Elsevier Inc. All rights reserved.