The protective effect of AIDS-related behavioral change among injection drug users: A cross-national study
The protective effect of AIDS-related behavioral change among injection drug users: A cross-national study
复制标题
DOI：
10.2105/ajph.86.12.1780
复制
发表时间：
1996-12-01
影响因子：
12.7
通讯作者：
Friedman, SR
中科院分区：
文献类型：
--
作者：
DesJarlais, DC;Friedmann, P;Friedman, SR
Objective.本研究评估了注射吸毒者自我报告的获得性免疫缺陷综合征（AIDS）行为改变与人类免疫缺陷病毒（HIV）血清状态之间的关系。研究样本涉及4419名注射吸毒者，他们来自北美、南美、欧洲、亚洲和澳大利亚11个城市的药物滥用治疗和非治疗机构。使用世界卫生组织多地点危险行为问卷，并获得血液或唾液样本进行HIV检测。受试者被问到：“自从你第一次听说艾滋病，你做过什么来避免感染艾滋病吗？”“结果。行为改变对HIV感染的保护优势比为0.50（95%置信区间= 0.42，0.59）。虽然各研究中心之间存在重要差异，但人口统计学和药物使用史亚组之间的关系保持一致。注射吸毒者：能够改变其艾滋病毒风险行为，并准确报告行为变化。这些行为变化与他们避免感染艾滋病毒有关。
Objective. This study assessed the relationship between self-reported acquired immunodeficiency syndrome (AIDS) behavioral change and human immunodeficiency virus (HIV) serostatus among injection drug users.Methods. The study sample involved 4419 injection drug users recruited from drug abuse treatment and nontreatment settings in 11 cities North America, South America, Europe, Asia, and Australia. The World Health Organization multisite risk behavior questionnaire was use, and either blood or saliva samples for HIV testing were obtained. Subjects were asked, ''Since you first heard about AIDS, have,you done anything to avoid getting-AIDS?''Results. The protective odds ratio for behavioral change against being infected with HIV was 0.50 (95% confidence interval = 0.42, 0.59). While there was important variation across sites, the relationship remained consistent across both demographic and drug use history subgroups.Conclusions. Injection drug users are: capable of modifying their HIV risk behaviors and reporting accurately on behavioral changes. These behavioral changes are associated with their avoidance of HIV infection.