Effect of short-duration hyperventilation during endotracheal suctioning on intracranial pressure in severe head-injured adults.
Effect of short-duration hyperventilation during endotracheal suctioning on intracranial pressure in severe head-injured adults.
复制标题
气管内吸痰期间短时过度通气对严重头部受伤成人颅内压的影响。
DOI：
10.1097/00006199-199707000-00003
复制
发表时间：
1997
期刊：
影响因子：
2.5
通讯作者：
Marion,DW
中科院分区：
文献类型：
--
作者：
Kerr,ME;Rudy,EB;Weber,BB;Stone,KS;Turner,BS;Orndoff,PA;Sereika,SM;Marion,DW
A repeated measures randomized within-group design was used to determine the effectiveness of controlled short-duration hyperventilation (HV) in blunting the increase of intracranial pressure (ICP) during endotracheal suctioning (ETS). A multimodal continuous real-time computerized data acquisition procedure was used to compare the effects of two HV ETS protocols on ICP, arterial pressure, cerebral perfusion pressure (CPP), heart rate, and arterial oxygen saturation in severe head-injured adult patients. The results indicated that short-duration HV for 1 minute, which decreases the PaCO 2, reduced ETS-induced elevations in ICP while maintaining CPP. However, it is not clear whether short-duration HV is neuroprotective, particularly in ischemic regions of the brain. Therefore, before a change in practice is implemented on the use of short-duration HV as a prophylactic treatment against ETS-induced elevations in ICP, additional questions on cerebral oxygen delivery and uptake need to be answered.
