Examining alcohol's contribution to the US African-American/White cirrhosis mortality differential from 1950 to 2002.
Examining alcohol's contribution to the US African-American/White cirrhosis mortality differential from 1950 to 2002.
复制标题
研究 1950 年至 2002 年间酒精对美国非裔美国人/白人肝硬化死亡率差异的影响。
DOI：
10.1093/alcalc/agt031
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Ye,Yu
中科院分区：
文献类型：
--
作者：
Kerr,WilliamC;Karriker-Jaffe,KatherineJ;Ye,Yu
目的：本研究的目的是估计酒精对美国种族和性别特异性年龄调整的肝硬化死亡率的总体影响，并考虑饮料的具体影响，代表随着时间的推移，饮酒模式的变化，比较国家与大型和小型非洲裔美国人/白色肝硬化死亡率differentials.Methods：使用1950年至2002年的一系列数据，人均酒精消费对肝硬化死亡率的影响，非洲裔美国人和白色男性和女性估计使用广义最小二乘面板模型的第一差分数据。格兰杰因果关系检验探讨了肝硬化mortality.Results的种族差异的地理模式：肝硬化死亡率显着正相关的酒精消费量，8-14%/l的乙醇的整体影响。这种影响是由精神驱动的，精神与非洲裔美国妇女和非洲裔美国男子的死亡率有更大的死亡率差异。这种差异首先出现在纽约，并蔓延到东北部和中西部states.Conclusion：酒精对肝硬化死亡率的贡献的差异表明，种族和性别的变化，在生活过程中的模式，大量消费，非法酒和烈酒的使用，以及出生队列的影响。
Aims:The aim of this study was to estimate the overall impact of alcohol on US race- and sex-specific age-adjusted cirrhosis mortality rates and to consider beverage-specific effects that represent changes in drinking patterns over time, comparing states with large and small African-American/White cirrhosis mortality differentials.Methods:Using series data from 1950 to 2002, the effects of per capita alcohol consumption on cirrhosis mortality for African American and White men and women were estimated using generalized least squares panel models on first-differenced data. Granger causality tests explored geographic patterning of racial differences in cirrhosis mortality.Results:Cirrhosis mortality was significantly positively related to apparent consumption of alcohol, with an overall impact of 8–14%/l of ethanol. This effect was driven by spirits which were more strongly associated with mortality for African-American women and for African-American men in states with larger mortality differentials. This disparity first emerged in New York and spread through the Northeast and into Midwestern states.Conclusion:Differences in the contribution of alcohol to cirrhosis mortality rates suggest variation by race and gender in life-course patterns of heavy consumption, illicit liquor and spirits use, as well as birth cohort effects.