Microscopic colitis: the tip of the iceberg?
Microscopic colitis: the tip of the iceberg?
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DOI：
10.1097/00042737-200211000-00007
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发表时间：
2002-11-01
影响因子：
2.1
通讯作者：
Price, AB
中科院分区：
文献类型：
--
作者：
Kitchen, PA;Levi, AJ;Price, AB
目的：目的是为了确定是否存在广泛的差异医院之间的诊断显微镜结肠炎和吸收临床资料。设计回顾性研究90例显微镜结肠炎患者，年龄在16和92岁之间，从11家医院在南方，方法设计一份调查问卷，收集所有新诊断为显微镜下结肠炎的患者的相关数据，在1990年1月至1996年12月期间，入选标准为水样腹泻、正常内镜检查和显微镜下结肠炎的组织学报告。然后要求并审查组织学切片。临床资料进行了分析，参考确诊diagnosis.Results在每家医院诊断的患者人数在0和30之间，中位数为6。对68例患者的组织学切片进行了审查。最终诊断为胶原性结肠炎、淋巴细胞性结肠炎和显微镜下结肠炎（未指定类型）的患者数量分别为37、18和7例。在31例患者（34%）有一个最近的历史，使用非甾体类抗炎药。结论这些数据证实，有广泛的医院变化的诊断显微镜下结肠炎。此外，未指定类型的小组可能与使用非甾体抗炎药有关。
Objectives The aims were to determine whether a wide variation exists between hospitals in the diagnosis of microscopic colitis and to assimilate clinical data.Design Retrospective study of 90 patients with microscopic colitis aged between 16 and 92 years from 11 hospitals in south-east England.Methods A questionnaire was designed to collect relevant data from all patients in whom a new diagnosis of microscopic colitis had been made at the source hospital between January 1990 and December 1996. The inclusion criteria were presentation with watery diarrhoea, a normal endoscopy and a histological report of microscopic colitis. Histology slides were then requested and reviewed. Clinical data were analysed with reference to the confirmed diagnosis.Results The number of patients diagnosed at each hospital ranged between zero and 30, with a median of six. Sixty-eight patients had histological slides reviewed. The numbers of patients with a final reviewed diagnosis of collagenous colitis, lymphocytic colitis and microscopic colitis, type undesignated, were 37,18 and seven respectively. In thirty-one patients (34%) there was a recent history of the use of non-steroidal anti-inflammatory drugs.Conclusions These data confirm that there is wide hospital variation in the diagnosis of microscopic colitis. Furthermore, the small group with the undesignated type may be associated with the use of non-steroidal anti-inflammatory drugs.