Direct IBD mapping: identical-by-descent mapping without genotyping.
Direct IBD mapping: identical-by-descent mapping without genotyping.
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直接 IBD 作图:无需基因分型的同源作图。
DOI:
10.1016/j.ygeno.2003.08.002
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发表时间:
2004
期刊:
影响因子:
4.4
通讯作者:
Cheung,VivianG
中科院分区:
文献类型:
--
作者:
Smirnov,Denis;Bruzel,Alan;Morley,Michael;Cheung,VivianG
Direct identical-by-descent (IBD) mapping is a technique, that combines genomic mismatch scanning (GMS) and DNA microarray technology, for mapping regions shared IBD between two individuals without locus-by-locus genotyping or sequencing. The lack of reagents has limited its widespread application. In particular, two key reagents have been limiting, 1) mismatch repair proteins MutS, L and H, and 2) genomic microarrays for identifying the genomic locations of the GMS-selected IBD fragments. Here, we describe steps that optimized the procedure and resources that will facilitate the development of direct IBD mapping.
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影响因子:
2.7
作者:
Feng,G;Winkler,ME
通讯作者:
Winkler,ME
影响因子:
30.8
作者:
Stanley F. Nelson;J. McCusker;Mark A. Sander;Y. Kee;P. Modrich;P. Brown
通讯作者:
Stanley F. Nelson;J. McCusker;Mark A. Sander;Y. Kee;P. Modrich;P. Brown
DOI:
10.1016/s0021-9258(19)49816-5
发表时间:
1992-06
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Karin G. AuS;K. Welsh;P. Modrich
通讯作者:
Karin G. AuS;K. Welsh;P. Modrich
影响因子:
7
作者:
Blazej, RG;Paegel, BM;Mathies, RA
通讯作者:
Mathies, RA
影响因子:
9.8
作者:
Mirzayans,F;Mears,AJ;Guo,SW;Pearce,WG;Walter,MA
通讯作者:
Walter,MA