Disseminated Mycobacterium marinum infection in a patient with rheumatoid arthritis receiving infliximab therapy
Disseminated Mycobacterium marinum infection in a patient with rheumatoid arthritis receiving infliximab therapy
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DOI：
10.1080/00365540902774599
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发表时间：
2009-01-01
影响因子：
--
通讯作者：
Decker, Catherine F.
中科院分区：
文献类型：
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作者：
Danko, Janine R.;Gilliland, William R.;Decker, Catherine F.
肿瘤坏死因子抑制剂是治疗风湿病的重要辅助疗法。这些药物增加了肉芽肿疾病的风险。我们提出一个病例的妇女严重类风湿关节炎的英夫利昔单抗发展多发结节性皮肤病变。活组织检查发现海洋分枝杆菌。通过治疗产生新的病变，需要手术切除。
Tumor necrosis factor- inhibitors are important adjunctive therapies for rheumatologic diseases. These agents increase the risk for granulomatous disease. We present a case of a woman with severe rheumatoid arthritis on infliximab who developed multiple nodular skin lesions. Biopsies grew Mycobacterium marinum. New lesions developed through therapy, necessitating surgical debulking.