Changes in hippocampal neuronal nuclei in response to environmental stimulation.
Changes in hippocampal neuronal nuclei in response to environmental stimulation.
复制标题
海马神经元核对环境刺激的反应发生变化。
DOI：
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复制
发表时间：
1979
影响因子：
2.2
通讯作者：
R. A. Cummins
中科院分区：
文献类型：
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作者：
R. Walsh;R. A. Cummins
据报道，当动物在丰富的感觉环境中饲养时，皮质神经元核的直径会增加，而不是剥夺感觉环境。本研究调查是否类似的神经元的变化发生在海马。雄性Wistar大鼠在断奶后80天在丰富或剥夺的环境中饲养。在该饲养期结束时，测量脑重量和海马神经元核直径。与分离的受试者相比，富集的受试者表现出更大的前脑：后脑比（3.7% p <0.05）。平均海马核尺寸无显着差异，但核大小的变异性更大的颗粒层的隔离对象（p <0.01）。有人提出，这种增加的变异性反映了这些神经元的环境限制的发展。
The diameter of cortical neuronal nuclei has been reported to increase when animals are reared in enriched, as opposed to deprived, sensory environments. The present study investigated whether analogous neuronal changes occur in the hippocampus. Male Wistar rats were reared in either an enriched or a deprived environment for 80 days after weaning. At the completion of this rearing period both brain weights and hippocampal neuronal nuclear diameters were measured. The enriched subjects exhibited a greater forebrain:hindbrain ratio (3.7% p less than 0.05) when compared to the isolated subjects. No significant differences in mean hippocampal nuclear dimensions could be detected but variability in nuclear size was greater in the stratum granulosum of the isolated subjects (p less than 0.01). It is proposed that this increased variability reflects an environmentally restricted development of these neurons.