Efficient Synthesis of Flaccidoside II, a Bioactive Component of Chinese Folk Medicine Di Wu
Efficient Synthesis of Flaccidoside II, a Bioactive Component of Chinese Folk Medicine Di Wu
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DOI：
10.1080/07328300903260192
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发表时间：
2009-11
影响因子：
1
通讯作者：
Qingchao Liu;Lei Zhang;Xiangpeng Li;Tiantian Guo;Peng Wang;Yingxia Li
中科院分区：
文献类型：
--
作者：
Qingchao Liu;Lei Zhang;Xiangpeng Li;Tiantian Guo;Peng Wang;Yingxia Li
从银莲花（Anemone flacaca Fr. Schmidt）干根茎中分离得到了一种有效的银莲花三萜皂苷——银莲花苷（flasecoside II）。我们在一锅反应中采用两个三氯乙酸糖基供体作为关键步骤。这篇文章有补充材料。请访问出版商的《碳水化合物化学杂志》网络版，获取以下免费补充资源：所有合成化合物的1H NMR， 13C NMR和HR质谱，2,6,9 -11和flac意外苷II (1)
A bidesmosidic triterpene saponin, flaccidoside II, which was isolated from Di Wu, a Chinese folk medicine from dry rhizome of Anemone flaccida Fr. Schmidt, was efficiently synthesized in a convergent approach. We employed two glycosyl trichloroacetimidate donors in a one-pot reaction as a key step. [Supplementary materials are available for this article. Go to the publisher's online edition of the Journal of Carbohydrate Chemistry for the following free supplemental resource(s): 1H NMR, 13C NMR and HR mass spectra for all synthesized compounds, 2, 6, 9-11, and Flaccidoside II (1)