Attention bias variability and symptoms of posttraumatic stress disorder.
Attention bias variability and symptoms of posttraumatic stress disorder.
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注意偏置变异性和创伤后应激障碍的症状。
DOI：
10.1002/jts.21899
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发表时间：
2014-04
影响因子：
3.3
通讯作者：
Charney DS
中科院分区：
文献类型：
--
作者：
Iacoviello BM;Wu G;Abend R;Murrough JW;Feder A;Fruchter E;Levinstein Y;Wald I;Bailey CR;Pine DS;Neumeister A;Bar-Haim Y;Charney DS
认知理论暗示焦虑症的病因学信息处理偏见。创伤后应激障碍（PTSD）的注意力偏差研究结果一直不一致，这表明对威胁的偏见和远离威胁的偏见。创伤后患者注意偏向的受试者内变异性可能是注意控制障碍和创伤后症状发展的一个有用标志。本研究报告了两个实验，探讨了创伤后与威胁相关的注意偏差、情绪和焦虑症状以及注意偏差的变异性。实验1包括3组横断面设计：（a）创伤后应激障碍，（B）创伤暴露无创伤后应激障碍，（c）健康对照无创伤或轴I诊断。与其他两组相比，PTSD组的注意力偏差变异性更大（= .23）;注意力偏差变异性与PTSD症状显著正相关（r = .37）。实验2评估战斗暴露和nonexposed士兵之前和部署期间。注意力偏差变异性在展开前没有区分组，但在展开过程中区分组（= 0.16）;仅在急性创伤后应激症状和急性抑郁症状组中观察到变异性增加。注意偏向变异性可能是一个有用的标记与创伤暴露后的情绪和焦虑症状相关的威胁线索的注意力障碍。
Cognitive theories implicate information-processing biases in the etiology of anxiety disorders. Results of attention-bias studies in posttraumatic stress disorder (PTSD) have been inconsistent, suggesting biases towards and away from threat. Within-subject variability of attention biases in posttraumatic patients may be a useful marker for attentional control impairment and the development of posttrauma symptoms. This study reports 2 experiments investigating threat-related attention biases, mood and anxiety symptoms, and attention-bias variability following trauma. Experiment 1 included 3 groups in a cross-sectional design: (a) PTSD, (b) trauma-exposed without PTSD, and (c) healthy controls with no trauma or Axis I diagnoses. Greater attention-bias variability was found in the PTSD group compared to the other 2 groups ( = .23); attention-bias variability was significantly and positively correlated (r = .37) with PTSD symptoms. Experiment 2 evaluated combat-exposed and nonexposed soldiers before and during deployment. Attention-bias variability did not differentiate groups before deployment, but did differentiate groups during deployment ( = .16); increased variability was observed in groups with acute posttraumatic stress symptoms and acute depression symptoms only. Attention-bias variability could be a useful marker for attentional impairment related to threat cues associated with mood and anxiety symptoms after trauma exposure.