Sleep and epilepsy

Sleep and epilepsy
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DOI:
10.1097/00019052-200004000-00010
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发表时间:
2000-04-01
影响因子:
4.8
通讯作者:
Bazil, Carl W.
Bazil, Carl W.
中科院分区:
医学2区
文献类型:
--
作者:
Bazil, Carl W.

文献摘要

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癫痫患者的睡眠障碍经常被忽视,但可能导致日间功能下降和癫痫发作活动增加。虽然复杂,但睡眠和癫痫之间的关系越来越清楚。睡眠,特别是深度非快速眼动睡眠,增加发作间期癫痫样活动。睡眠增加某些类型的癫痫发作和部分性癫痫发作的泛化率,然而,快速眼动睡眠似乎抑制癫痫发作。睡眠障碍,尤其是睡眠呼吸暂停,会加剧癫痫发作。反过来,癫痫发作会扰乱睡眠结构,特别是快速眼动睡眠。了解这些关系对癫痫发作控制和最大限度地提高癫痫患者的生活质量非常重要。
Sleep disturbance in patients with epilepsy is frequently overlooked, but may contribute to decreased daytime functioning and increased seizure activity. Although complicated, the relationship between sleep and epilepsy is becoming clearer. Sleep, and particularly deep non-rapid-eye-movement sleep, increase interictal epileptiform activity. Sleep increases certain seizure types and the rate of generalization of partial seizures, however rapid-eye-movement sleep seems to suppress seizures. Sleep disorders, particularly sleep apnea, exacerbate seizures. Seizures, in turn, can disrupt sleep structure, particularly rapid-eye-movement sleep. An understanding of these relationships is important in seizure control and in maximizing the quality of life for patients with epilepsy.