GROWTH OF MOUSE MAMMARY GLANDS IN VIVO AFTER MONOLAYER CULTURE
GROWTH OF MOUSE MAMMARY GLANDS IN VIVO AFTER MONOLAYER CULTURE
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DOI：
10.1126/science.149.3684.634
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发表时间：
1965-01-01
期刊：
影响因子：
56.9
通讯作者：
DEOME, KB
中科院分区：
文献类型：
--
作者：
DANIEL, CW;DEOME, KB
在原代细胞培养中生长的小鼠乳腺组织未显示出母体组织的特化特征。当将这些培养细胞植入无乳腺腺泡的乳腺脂肪垫时，不仅其中一些培养细胞能够生长并产生正常的乳腺增生，而且一些增生形成的腺体还表现出多种由培养诱导的异常。
Mouse mammary tissue grown in primary cell culture did not display specialized characteristics of the parent tissue. When implanted into gland-free mammary fat pads, not only did some of these cultured cells grow and produce normal mammary out-growths, but some of the outgrowths formed glands which displayed a variety of culture-induced abnormalities.