Interactions between climate factors and air pollution on daily HFMD cases: A time series study in Guangdong, China
Interactions between climate factors and air pollution on daily HFMD cases: A time series study in Guangdong, China
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气候因素与空气污染对手足口病日常病例的相互作用：中国广东省的时间序列研究
DOI：
10.1016/j.scitotenv.2018.11.391
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发表时间：
2019-03-15
影响因子：
9.8
通讯作者：
Hao, Yuantao
中科院分区：
文献类型：
--
作者：
Du, Zhicheng;Lawrence, Wayne R.;Hao, Yuantao
背景：先前的研究表明，气候因素和空气污染与手足口病（HFMD）流行有关。方法：收集2009 - 2012年广东省手足口病日发病数，分析手足口病发病与空气污染的关系。我们使用分布滞后非线性模型来评估气候因素和空气污染对手足口病病例的影响。气候因子的影响按空气污染分层，以检查空气质量指数（AQI）和温度的交互作用，以及相对湿度。此外，我们探讨了性别groups.Results的变异性：我们观察到手足口病病例和环境因素，包括温度，相对湿度和空气质量指数之间的关联。相对危险度（RR）在温度和空气质量指数中等水平、相对湿度高水平时最高。统计分析了空气质量指数与气候因子的交互作用对手足口病发病的影响。与低水平温度（= 23.5摄氏度）相比，在空气质量“良好“的日子（AQI 46）的RR为1.486（95%CI：1.469，1.503）。相对湿度高（>77%）在空气质量“良好“日的RR为1.082（95% CI：1.076，1.089），在空气质量“中等”日的RR为1.039（95% CI：1.033，1.046）。的协会和相互作用仍然强大的男性和女性。结论：我们的研究结果表明，气候因素和空气污染施加滞后和非线性的影响手足口病流行。气候因素对健康的影响可能因AQI而异。我们的研究对于有针对性的预防和控制是实用和有用的，并提供了基于环境的证据。(c)2018 Elsevier B. V.版权所有。
Background: Prior studies have shown that climate factors and air pollution are associated with hand, foot, and mouth disease (HFMD) epidemics. However, the interaction between air pollution and climate factors remains unknown.Methods: Daily HFMD counts from2009 through 2012 in Guangdongwere collected. We used distributed lag non-linear models to assess the associations of climate factors and air pollution on HFMD cases. The effects of climate factors were stratified by air pollution stratum to examine the interaction effect of air quality index (AQI) and temperature, as well as relative humidity. In addition, we explored the variability across gender groups.Results: We observed associations between HFMD cases and environmental factors, including temperature, relative humidity, and AQI. The highest relative risks (RR) were observed at themiddle level of temperature and AQI, and high level of relative humidity. The effects for the interaction between AQI and climate factors on HFMD cases were also statistically observed. Compared with low level temperatures (= 23.5 degrees C) had a RR of 1.486 (95% CI: 1.469,1.503) on days with "good"air quality (AQI 46). For relative humidity, the high level (>77%) had a RR of 1.082 (95% CI: 1.076,1.089) on days with "good"air quality, and RR of 1.039 (95% CI: 1.033,1.046) on days with "moderate" air quality. The associations and the interactions remained robust for males and females.Conclusions: Our findings indicate that climate factors and air pollution imposed lagged and non-linear effects on HFMD epidemics. The effects of climate factors on health potentially vary by AQI. Our study is practical and useful for targeted prevention and control, and provides environmental-based evidence. (c) 2018 Elsevier B.V. All rights reserved.