Structural and functional analyses of bacterial lipopolysaccharides
Structural and functional analyses of bacterial lipopolysaccharides
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DOI:
10.1016/s1286-4579(02)01612-x
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发表时间:
2002-07-01
影响因子:
5.8
通讯作者:
Haeffner-Cavaillon, N
中科院分区:
文献类型:
--
作者:
Caroff, M;Karibian, D;Haeffner-Cavaillon, N
Bacterial lipopolysaccharides (LPSs) are powerful immunomodulators in infected hosts, and may cause endotoxic shock. Most of them share a common architecture but vary considerably in structural motifs from one genus, species, and strain to another. Cells of the innate immune response recognize evolutionarily conserved LPS molecular patterns of endotoxins and structural details thereby greatly influencing their response. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.