Antibacterial activities of selected edible plants extracts against multidrug-resistant Gram-negative bacteria.
Antibacterial activities of selected edible plants extracts against multidrug-resistant Gram-negative bacteria.
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选定的可食用植物提取物针对多药抗革兰氏阴性细菌的抗菌活性。
DOI：
10.1186/1472-6882-13-164
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发表时间：
2013-07-10
影响因子：
--
通讯作者：
Kuete V
中科院分区：
文献类型：
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作者：
Djeussi DE;Noumedem JA;Seukep JA;Fankam AG;Voukeng IK;Tankeo SB;Nkuete AH;Kuete V
为了应对对许多抗生素具有抗性的细菌（也称为多药耐药（MDR）细菌）的繁殖，发现新的和更有效的抗菌剂是原始的。本研究的目的是评价7种食用植物（猴面包树、白花猴面包树、多花猴面包树、番荔枝）的抗菌活性。mannii、木槿、罗勒和罗望子）。使用所述方法对所研究的提取物进行植物化学筛选，同时将液体肉汤微量稀释用于针对27种革兰氏阴性菌的所有抗微生物测定。植物化学测试的结果表明，所有测试的提取物含有酚类和三萜类，其他类别的化学品被选择性地存在。所研究的提取物显示出不同程度的抗菌活性。A. digitata，H. sabdarifa、黑腹拟步行虫A. polyanthum，多花菊A. alboviolaceum和O.对27种供试细菌的抑制率分别为81.48%、66.66%、62.96%、55.55%和55.55%。A. polyanthum对E.产气杆菌EA 294的最低记录最小抑制浓度（MIC）为32 μg/ml。本工作的结果提供了有用的基线信息的潜在用途的研究食用植物在对抗敏感和MDR表型。
In response to the propagation of bacteria resistant to many antibiotics also called multi-drug resistant (MDR) bacteria, the discovery of new and more efficient antibacterial agents is primordial. The present study was aimed at evaluating the antibacterial activities of seven Cameroonian dietary plants (Adansonia digitata, Aframomum alboviolaceum, Aframomum polyanthum, Anonidium. mannii, Hibiscus sabdarifa, Ocimum gratissimum and Tamarindus indica). The phytochemical screening of the studied extracts was performed using described methods whilst the liquid broth micro dilution was used for all antimicrobial assays against 27 Gram-negative bacteria. The results of the phytochemical tests indicate that all tested extracts contained phenols and triterpenes, other classes of chemicals being selectively present. The studied extracts displayed various degrees of antibacterial activities. The extracts of A. digitata, H. sabdarifa, A. polyanthum, A. alboviolaceum and O. gratissimum showed the best spectra of activity, their inhibitory effects being recorded against 81.48%, 66.66%, 62.96%, 55.55%, and 55.55% of the 27 tested bacteria respectively. The extract of A. polyanthum was very active against E. aerogenes EA294 with the lowest recorded minimal inhibitory concentration (MIC) of 32 μg/ml. The results of the present work provide useful baseline information for the potential use of the studied edible plants in the fight against both sensitive and MDR phenotypes.