Impaired physical health among methamphetamine users in comparison with the general population: the role of methamphetamine dependence and opioid use
Impaired physical health among methamphetamine users in comparison with the general population: the role of methamphetamine dependence and opioid use
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DOI：
10.1080/09595230801914776
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发表时间：
2008-01-01
影响因子：
3.8
通讯作者：
Proudfoot, Heather
中科院分区：
文献类型：
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作者：
McKetin, Rebecca;Kelly, Erin;Proudfoot, Heather
瞄准研究与普通人群相比，甲基苯丙胺使用者社区样本中身体健康损害的程度，以及与这一群体中损害相关的因素。法对悉尼309名经常使用甲基苯丙胺的人进行了横断面调查。使用SF-12量表（SF-12）测量身体健康受损（评分< 40）。SF-12的与健康匹配的一般人群数据来自澳大利亚国家心理健康和幸福调查。结果与澳大利亚普通人群相比，参与者的身体健康受损患病率更高（20% vs. 10%，p < 0.05），但这种影响仅发生在24岁以上的甲基苯丙胺依赖者中（25-34岁，23% vs. 10%; 35-44岁，41% vs. 12%）。在调整了年龄和其他混杂因素后，甲基苯丙胺依赖仍然显著预测身体健康受损。阿片类药物治疗也与身体健康状况不佳密切相关，占身体受损参与者的63%。与身体健康受损相关的其他因素是女性，受教育时间少于10年，以前被诊断患有焦虑症（p < 0.05）。结论甲基苯丙胺使用者比一般人群更有可能报告身体健康受损，但这种损害是依赖该药物的老年甲基苯丙胺使用者所特有的，特别是那些参加阿片类药物治疗的人。
Aim. To examine the extent of physical health impairment among a community sample of methamphetamine users in comparison with the general population, and factors associated with impairment among this group. Method. A cross-sectional survey of 309 regular methamphetamine users from Sydney. The Physical Component Scale of the Short Form 12 (SF-12) was used to measure impairment in physical health (score < 40). Age-matched general population data for the SF-12 were derived from the Australian National Survey of Mental Health and Well-Being. Results. Participants had a higher prevalence of impaired physical health compared to the Australian general population (20% vs. 10%, p < 0.05), but this effect occurred among only dependent methamphetamine users over 24 years of age (25-34 years, 23% vs. 10%; 35-44 years, 41% vs. 12%). Methamphetamine dependence remained significantly predictive of impaired physical health after adjusting for age and other confounding factors. Opioid pharmacotherapy was also related strongly to poor physical health, accounting for 63% of participants with physical impairment. Other factors associated with impaired physical health were being female, having less than 10 years of schooling, and having been diagnosed previously with an anxiety disorder (p < 0.05). Conclusion. Methamphetamine users are more likely to report impaired physical health than the general population, but this impairment is specific to older methamphetamine users who are dependent on the drug, particularly those who are enrolled in opioid pharmacotherapy.