Potential of tomotherapy for total scalp treatment
Potential of tomotherapy for total scalp treatment
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DOI：
10.1016/s0360-3016(01)02593-7
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发表时间：
2002-02-01
影响因子：
7
通讯作者：
Chao, KSC
中科院分区：
文献类型：
--
作者：
Locke, J;Low, DA;Chao, KSC
目的：全头皮放射治疗是需要在各种临床情况。我们比较了传统的侧向光子电子（LPE）技术与断层治疗（调强放射治疗[IMRT]）。方法和材料：默克尔细胞癌患者在我们的机构使用传统的治疗技术。治疗计划采用传统的三维治疗计划和调强放射治疗。临床目标体积包括整个头皮组织体积到下方颅骨表面，以及双侧颈部的浅颈和深颈淋巴结。为了提供一致的IMRT和三维常规治疗计划之间的比较，剂量分布进行了归一化，使90%的目标体积接收处方dose.Results：检查我们的结果显示了一个可接受的剂量体积直方图和足够的覆盖范围的临床目标体积使用传统的LPE技术。调强放射治疗计划提供了一个更均匀的剂量的目标体积，但是，临界结构剂量均匀高于传统的治疗planne.Conclusions：调强放射治疗计划导致大量的剂量的透镜，大脑和轨道，使其临床上不可接受的LPE技术相比。总体而言，LPE技术具有上级优势。(C)2002年爱思唯尔科学公司
Purpose: Total scalp radiotherapy is required in a variety of clinical situations. We compared conventional lateral photon-electron (LPE) technique with tomotherapy (intensity-modulated radiotherapy [IMRT]).Methods and Materials: A patient with Merkel cell carcinoma was treated at our institution using conventional treatment techniques.. Treatment plans were conducted using conventional three-dimensional treatment planning and IMRT. The clinical target volume included the entire scalp tissue volumes to the surface of underlying cranial bone, as well as superficial and deep neck nodes in the bilateral neck. To provide a consistent comparison between the IMRT and three-dimensional conventional treatment plans, the dose distributions were normalized such that 90% of the target volumes received the prescription dose.Results: Examination of our results revealed an acceptable dose-volume histogram and adequate coverage of the clinical target volume using the conventional LPE technique. The IMRT plan provided a more homogeneous dose to the target volume; however, critical structure doses were uniformly higher than for the conventional treatment plan.Conclusions: The IMRT plan resulted in a substantial dose to the lens, brain, and orbit, making it clinically unacceptable compared with the LPE technique. Overall, the LPE technique was superior. (C) 2002 Elsevier Science Inc.