Therapeutic Opportunities for Self-Control Repair in Addiction and Related Disorders: Change and the Limits of Change in Trans-Disease Processes.
Therapeutic Opportunities for Self-Control Repair in Addiction and Related Disorders: Change and the Limits of Change in Trans-Disease Processes.
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DOI：
10.1177/2167702614541260
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发表时间：
2015-01-01
期刊：
影响因子：
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通讯作者：
Wilson AG
中科院分区：
文献类型：
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作者：
Bickel WK;Quisenberry AJ;Moody L;Wilson AG
当代的神经经济学方法假设，自我控制失败的原因是药物吞并了正常的学习机制，这些机制产生了病理性的奖励处理，并扭曲了决策，这是两个评估系统失调的结果。强调不同疾病和障碍的共同过程与当代假定独特的疾病病因和治疗方法是不一致的。研究跨疾病过程可以确定在多种疾病状态下工作的机制，并确定影响一种疾病状态下的过程的因素是否适用于所有疾病状态。在本文中，我们回顾了自我控制失败的对偶模型，竞争神经行为决策系统方法，延迟折扣与这两个系统相对控制的关系，以及执行系统可以加强的证据。未来的研究，可能导致更有力的干预措施，以改善执行系统和潜在的制约因素修复自我控制的失败进行了讨论。
Contemporary neuro-economic approaches hypothesize that self-control failure results from drugs annexing normal learning mechanisms that produce pathological reward processing and distort decision-making as a result from the dysregulation of two valuation systems. An emphasis on processes shared across different diseases and disorders is at odds with the contemporary approach that assumes unique disease etiologies and treatments. Studying trans-disease processes can identify mechanisms that operate in multiple disease states and ascertain if factors that influence processes in one disease state may be applicable to all disease states. In this paper we review the dual model of self-control failure, the Competing Neurobehavioral Decision Systems approach, the relationship of delay discounting to the relative control of these two systems, and evidence that the executive system can be strengthened. Future research that could result in more potent interventions for executive system improvement and potential constraints on the repair of self-control failure are discussed.