Laser Doppler flowmetry in burn wounds.
Laser Doppler flowmetry in burn wounds.
复制标题
激光多普勒血流计在烧伤创面中的应用。
DOI：
10.1097/00004630-199507000-00003
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Baxter,C
中科院分区：
文献类型：
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作者：
Atiles,L;Mileski,W;Purdue,G;Hunt,J;Baxter,C
传统的根据外观和感觉对创面进行临床评估来判断烧伤深度的方法仍然被广泛使用，但受检查人员的个体差异的影响。除了烧伤创面管理的临床困难外，对创面评估的观察者依赖性使烧伤创面治疗的临床试验复杂化。新设计的多道探头激光多普勒血流计被用来测量烧伤创面的血流灌注，作为预测创面结局的工具。在不到21天内自然愈合的创面显示出比那些需要切除和移植或在烧伤后第21天仍未愈合的创面更高的平均灌注量。激光多普勒血流仪在烧伤后第1天和第3天对未愈合创面的阳性预测值为100%。这些数据表明激光多普勒血流仪是一种潜在的烧伤创面评估工具。
Traditional methods for judgment of burn depth by clinical evaluation of the wound based on appearance and sensation remain in wide use but are subject to individual variation by examiner. In addition to the clinical difficulties with burn wound management, observer dependency of wound assessment complicates clinical trials of burn wound therapy. A laser Doppler flowmeter with a newly designed multichannel probe was used to measure burn wound perfusion as a tool to predict wound outcome. Wounds that healed spontaneously in fewer than 21 days showed higher average perfusion levels than those that required excision and grafting or that were not healed by day 21 after the burn. Laser Doppler flowmetry had a positive predictive value of 100% for nonhealing wounds on postburn days 1 and 3. These data suggest that laser Doppler flowmetry is a potentially useful tool for burn wound assessment.