Isolation of new neolignans and an unusual meroterpenoid from Piper cabagranum
Isolation of new neolignans and an unusual meroterpenoid from Piper cabagranum
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DOI：
10.3389/fntpr.2023.1332436
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发表时间：
2024-01
期刊：
影响因子：
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通讯作者：
Celso R. de Oliveira;Zachary D. Ledvina;M. D. Leonard;Samuel O. Odoh;Craig D. Dodson;Christopher S. Jeffrey-Christophe
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文献类型：
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作者：
Celso R. de Oliveira;Zachary D. Ledvina;M. D. Leonard;Samuel O. Odoh;Craig D. Dodson;Christopher S. Jeffrey-Christophe
从卡巴格兰胡椒（Piper cabagranum）（哥斯达黎加）的叶中分离到一种新的部分萜类化合物卡巴格兰宁D和相关的新木脂素卡巴格兰宁A-C。卡巴格兰宁A-C代表了从胡椒属植物中分离出的第一个3，3 ′-新木脂素的例子，而部分萜类化合物卡巴格兰宁D显示出前所未有的未取代的苯基丙烯酮和α-水芹烯的狄尔斯-阿尔德共轭物。这些化合物的完整结构的详细说明和讨论其潜在的生物合成的关系。
A novel meroterpenoid cabagranin D was isolated with related neolignans cabagranins A–C from the leaves of Piper cabagranum (Costa Rica). Cabagranins A–C represent the first examples of 3,3′-neolignans isolated from the plant genus Piper, and the meroterpenoid cabagranin D displays an unprecedented Diels–Alder conjugate of an unsubstituted phenylpropenone and α-phellandrene. Details of the full structural elucidation of these compounds and a discussion of their potential biosynthetic relationships are presented.