PUBERTAL ENDOCRINOLOGY OF YELLOW BABOON (PAPIO-CYNOCEPHALUS) - PLASMA TESTOSTERONE, TESTIS SIZE, BODY-WEIGHT, AND CROWN-RUMP LENGTH IN MALES
PUBERTAL ENDOCRINOLOGY OF YELLOW BABOON (PAPIO-CYNOCEPHALUS) - PLASMA TESTOSTERONE, TESTIS SIZE, BODY-WEIGHT, AND CROWN-RUMP LENGTH IN MALES
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DOI：
10.1002/ajp.1350110308
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发表时间：
1986-01-01
影响因子：
2.4
通讯作者：
KUEHL, TJ
中科院分区：
文献类型：
--
作者：
CASTRACANE, VD;COPELAND, KC;KUEHL, TJ
一项横断面研究(n=99)是3周龄至10岁的雄性狒狒(Papio Cynocephalus)。比较血清睾酮和睾丸大小与体重和冠臀长的关系。狒狒的青春期发作发生在3-4岁；因此，对数据进行了分析，分三组：0-3岁；3-4岁；以及大于4岁。睾丸体积指数在3岁前最小幅度增加。在3到4岁之间，睾丸生长有一个增加(P<；0.05)，然后在4岁之后恢复到青春期前的比率。血浆睾酮从出生到3岁呈下降趋势。在3到4岁之间，睾丸激素水平升高(P<；0.05)。其水平在4岁以后保持不变。体重在前3年呈线性增长，随后在3至4岁之间体重增加率增加(P<；.05)。4岁以后，体重继续增加，但速度低于前两个时期。在最初的3年中，观察到了树冠臀长的线性增长。在3-4岁之间，树冠臀长略有增加(P>；.06)，4岁后接近于零。这些数据表明，雄性狒狒的青春期发育与人类有许多相似之处。雄性狒狒似乎适合研究生殖和内分泌发育，以及与人类雄性青春期生长突增有关的因素。
A cross-sectional study (n=99) was made of male baboons (Papio cynocephalus) aged 3 weeks to > 10 years. Serum testosterone and testicular size were compared with body weight and crown-rump length. Pubertal onset in baboons occurs at 3-4 years of age; data were analyzed, therefore in three groups: 0-3 years; 3-4 years; and greater than 4 years. Testicular volume index increased minimally prior to 3 years of age. Between 3 and 4 years of age, there was an increase (P < .05) in testicular growth, which was followed after 4 years of age by a return to the prepubertal rate. Plasma testosterone decreased from birth to 3 years of age. Between 3 and 4 years of age, there was an increase (P < .05) in testosterone. The levels of which remained unchanged after 4 years of age. A linear increase in body weight was observed for the first 3 years which was followed by an increase (P < .05) in the rate of weight gain between 3 and 4 years of age. After 4 years of age, body weight continued to increase but at a rate less than those of the two earlier periods. A linear increase in crown-rump length was observed over the first 3 years. Between 3 and 4 years of age there was a slight increase (P > .06) in crown-rump length, which approached zero after 4 years of age. These data demonstrate many similarities between the pubertal development of male baboons and humans. Male baboons appear to be appropriate for the study of reproductive and endocrine development and the factors involved in the pubertal growth spurt of the human male.