Results of a Multidisciplinary Treatment Program in 3-Year-Old to 5-Year-Old Overweight or Obese Children A Randomized Controlled Clinical Trial
Results of a Multidisciplinary Treatment Program in 3-Year-Old to 5-Year-Old Overweight or Obese Children A Randomized Controlled Clinical Trial
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DOI：
10.1001/archpediatrics.2012.1638
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发表时间：
2012-12-01
影响因子：
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通讯作者：
Sauer, Pieter J. J.
中科院分区：
文献类型：
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作者：
Bocca, Gianni;Corpeleijn, Eva;Sauer, Pieter J. J.
目的：评估多学科干预方案对3至5岁超重和肥胖儿童的效果，并与常规护理方案进行比较。设计：2006年10月至2008年3月进行随机对照临床试验。环境：格罗宁根大学医学中心比阿特丽克斯儿童医院肥胖儿童专家中心。参与者：75名3至5岁的儿童（29名超重，46名肥胖）。干预：多学科干预方案vs常规护理方案。在16周计划开始和结束时以及干预开始后12个月进行人体测量，并通过生物电阻抗分析和超声检查确定身体成分。主要结局指标：与常规护理组相比，多学科干预组的实际体重减轻、体重指数（BMI，以体重（公斤）除以身高（米）的平方计算）变化、BMI z评分、体脂率和内脏脂肪。结果：在治疗方案结束时，多学科干预组儿童BMI、BMI z评分、腰围z评分较常规护理组儿童下降幅度更大。在12个月时，干预组儿童的BMI、BMI z评分、腰围和腰围z评分与常规护理组儿童相比下降幅度更大。内脏脂肪呈大幅度下降趋势。结论：对3- 5岁超重和肥胖儿童进行多学科干预对人体测量和身体成分有有益的影响。在干预开始12个月后，积极的影响仍然存在。试验注册：isrctn.org标识符：ISRCTN47185691
Objective: To assess the effects of a multidisciplinary intervention program for 3-year-old to 5-year-old overweight and obese children compared with a usual-care program.Design: Randomized controlled clinical trial conducted from October 2006 to March 2008.Setting: Groningen Expert Center for Kids with Obesity at Beatrix Children's Hospital, University Medical Center Groningen.Participants: Seventy-five children (29 overweight, 46 obese) aged 3 to 5 years.Intervention: A multidisciplinary intervention program vs a usual-care program. Anthropometry was performed and body composition was determined by bioelectrical impedance analysis and ultrasonography at the start and end of the 16-week program and 12 months after starting the intervention.Main Outcome Measures: The actual weight reduction, change in body mass index (BMI, calculated as weight in kilograms divided by height in meters squared), BMI z score, body fat percentage, and visceral fat in the multidisciplinary intervention group compared with a usual-care group.Results: At the end of the treatment program, children in the multidisciplinary intervention group showed a greater decrease in BMI, BMI z score, and waist circumference z score compared with children in the usual-care group. At 12 months, children in the intervention group showed greater decreases in BMI, BMI z score, waist circumference, and waist circumference z score compared with children in the usual-care group. Visceral fat showed a trend toward a higher decrease.Conclusions: A multidisciplinary intervention program in 3-year-old to 5-year-old overweight and obese children had beneficial effects on anthropometry and body composition. The positive effects were still present 12 months after the start of the intervention.Trial Registration: isrctn.org Identifier: ISRCTN47185691