Comparison of HIV infection risk behaviors among injection drug users from East and West Coast US cities
Comparison of HIV infection risk behaviors among injection drug users from East and West Coast US cities
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DOI：
10.1093/jurban/jth112
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发表时间：
2004-06-01
影响因子：
6.6
通讯作者：
Holmberg, SD
中科院分区：
文献类型：
--
作者：
Garfein, RS;Monterroso, ER;Holmberg, SD
本研究评估了行为差异是否解释了美国东海岸三个城市与西海岸两个城市注射吸毒者（IDUs）中较高的人类免疫缺陷病毒（HIV）血清阳性率。在半年一次的面对面访谈中收集了社会人口学、性和注射信息。将来自纽约市、马里兰州的巴尔的摩和康涅狄格州的纽黑文的基线数据与来自加州的洛杉矶和加州的圣何塞的数据进行比较。在1,528名东海岸和1,149名西海岸参与者中，HIV血清阳性率分别为21.5%和2.3%（比值比[OR] 11.9; 95%置信区间[CI] 7.9-17.8）。艾滋病毒危险行为在两个海岸的注射吸毒者中很常见，有几种在西海岸的参与者中更常见。调整潜在的风险因素，东（与西）海岸的居住仍然与艾滋病毒状态高度相关（调整OR 12.14; 95% CI 7.36-20.00）。东海岸和西海岸城市之间的HIV血清阳性率差异并不反映自我报告的注射或性风险行为差异。这表明必须考虑其他因素，如注射或性伴侣感染艾滋病毒的可能性。西海岸需要采取预防措施，以减少ID Us中与艾滋病毒相关的风险行为，还需要进一步努力减少东海岸的艾滋病毒发病率。
This study assessed whether behavioral differences explained higher human immunodeficiency virus (HIV) seroprevalence among injection drug users (IDUs) in three East Coast versus two West Coast cities in the United States. Sociodemographic, sexual, and injecting information were collected during semiannual face-to-face interviews. Baseline data from New York City; Baltimore, Maryland; and New Haven, Connecticut, were compared with data from Los Angeles, California, and San Jose, California. Among 1,528 East Coast and 1,149 West Coast participants, HIV seroprevalence was 21.5% and 2.3%, respectively (odds ratio [OR] 11.9; 95% confidence interval [CI] 7.9-17.8). HIV risk behaviors were common among IDUs on both coasts, and several were more common among West Coast participants. Adjusting for potential risk factors, East (vs. West) Coast of residence remained highly associated with HIV status (adjusted OR 12.14; 95% CI 7.36-20.00). Differences in HIV seroprevalence between East and West Coast cities did not reflect self-reported injection or sexual risk behavior differences. This suggests that other factors must be considered, such as the probability of having HIV-infected injection or sexual partners. Prevention efforts are needed on the West Coast to decrease HIV-associated risk behaviors among ID Us, and further efforts are also needed to reduce HIV incidence on the East Coast.