Diaphragm Adaptations Elicited by Severe Chronic Obstructive Pulmonary Disease: Lessons for Sports Science

Diaphragm Adaptations Elicited by Severe Chronic Obstructive Pulmonary Disease: Lessons for Sports Science
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严重慢性阻塞性肺疾病引起的隔膜适应:运动科学的教训

DOI:
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发表时间:
2001
影响因子:
5.7
通讯作者:
Neal Rubinstein
Neal Rubinstein
中科院分区:
医学2区
文献类型:
--
作者:
S. Levine;Taitan Nguyen;J. Shrager;Larry R. Kaiser;V. Camasamudram;Neal Rubinstein

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Levine S.,Nguyen,T.,Shrager,J.,Kaiser,L.,CAMASAMUDRAM,V.和Rubinstein,N.严重慢性阻塞性肺疾病引起的横隔膜适应:体育科学课程。用力。体育科学。修订本,第29卷,第1期,第71-75页,2001年。在人类中,横隔膜通过(A)纤维类型和肌原纤维蛋白的快速到缓慢的转变和(B)线粒体氧化酶的活性增加来适应严重的慢性阻塞性肺疾病。我们认为,几十年的渐进式耐力训练是这些适应的原因。
LEVINE, S., NGUYEN, T., SHRAGER, J., KAISER, L., CAMASAMUDRAM, V., and RUBINSTEIN, N. Diaphragm adaptations elicited by severe chronic obstructive pulmonary disease: lessons for sports science. Exerc. Sport Sci. Rev., Vol. 29, No. 1, pp 71-75, 2001. In humans, the diaphragm adapts to severe chronic obstructive pulmonary disease with (a) fast-to-slow transformations of the fiber types and myofibrillar proteins and (b) increases in the activity of mitochondrial oxidative enzymes. We suggest that progressive endurance training over several decades accounts for these adaptations.