Transmission of Mycobacterium tuberculosis between Farmers and Cattle in Central Ethiopia

Transmission of Mycobacterium tuberculosis between Farmers and Cattle in Central Ethiopia
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DOI:
10.1371/journal.pone.0076891
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发表时间:
2013-10-10
期刊:
影响因子:
3.7
通讯作者:
Berg, Stefan
Berg, Stefan
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Ameni, Gobena;Tadesse, Konjit;Berg, Stefan

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背景:结核分枝杆菌(M.在埃塞俄比亚,农民和他们的牛之间可能存在结核病)复合体。方法/主要发现:在埃塞俄比亚混合型多用途养牛区对287户农户进行了研究(146户肺结核患者和141户无肺结核患者)和287个畜群,033头属于这些家庭的牛,以评估牛和农民之间的结核病传播。访谈,细菌学检查和分子分型用于人类受试者,而比较皮内结核菌素(CIDT)试验,尸检和细菌学检查,分子分型用于动物研究。CIDT反应者的群体患病率为9.4%,
Background: Transmission of Mycobacterium tuberculosis (M. tuberculosis) complex could be possible between farmers and their cattle in Ethiopia.Methodology/Principal Findings: A study was conducted in mixed type multi-purposes cattle raising region of Ethiopia on 287 households (146 households with case of pulmonary tuberculosis (TB) and 141 free of TB) and 287 herds consisting of 2,033 cattle belonging to these households to evaluate transmission of TB between cattle and farmers. Interview, bacteriological examinations and molecular typing were used for human subjects while comparative intradermal tuberculin (CIDT) test, post mortem and bacteriological examinations, and molecular typing were used for animal studies. Herd prevalence of CIDT reactors was 9.4% and was higher (p