Diagnosis of hepatobiliary disease in infants and children with Tc-99m-diethyl-IDA imaging.
Diagnosis of hepatobiliary disease in infants and children with Tc-99m-diethyl-IDA imaging.
复制标题
Tc-99m-二乙基-IDA 成像诊断婴儿和儿童肝胆疾病。
DOI：
10.1097/00003072-198107000-00003
复制
发表时间：
1981
影响因子：
10.6
通讯作者：
Lilly,JR
中科院分区：
文献类型：
--
作者：
Ohi,R;Klingensmith3rd,WC;Lilly,JR
对13例42天~14岁的婴幼儿肝胆疾病患者进行了~(99m)Tc-二乙基-IDA肝胆显像。5例胆道闭锁，4例胆管发育不良，2例新生儿肝炎，1例α1抗胰蛋白酶缺乏和先天性肝纤维化。胆道闭锁(完全性胆道梗阻)与其他形式的儿童肝胆疾病的TC-99m-二乙基-IDA显像能准确地鉴别，前者无肠道放射性，后者有肠道放射性。此外，4例胆管发育不良患者中有2例实质传输不均匀，1例先天性肝纤维化患者可能有肝内囊肿。综上所述，这些初步数据表明，99m-二乙基IDA提供了以前L-131-孟加拉玫瑰所没有的信息；这些信息可能在儿童肝胆疾病的无创性评估中有用。
Thirteen infants and children from 42 days to 14 years old with hepatobiliary disease underwent Tc-99m-diethyl-IDA hepatobiliary imaging. Five patients had biliary atresia, four had biliary hypoplasia, two had neonatal hepatitis, and there were single examples of alpha-1-antitrypsin deficiency and congenital hepatic fibrosis. Tc-99m-diethyl-IDA imaging accurately differentiated biliary atresia (complete bile duct obstruction) from other forms of childhood hepatobiliary disease by demonstrating no intestinal radioactivity in the former and the presence of intestinal radioactivity in the latter. In addition, two of four patients with biliary hypoplasia had nonhomogeneous parenchymal transit, and the one patient with congenital hepatic fibrosis showed possible intrahepatic cysts. In conclusion, these preliminary data indicate that Tc-99m-diethyl-IDA provides information not previously available with l-131-rose bengal; this information is likely to be useful in the noninvasive evaluation of childhood hepatobiliary disease.