The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004
The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004
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DOI：
10.1093/eurheartj/ehl196
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发表时间：
2006-10-01
影响因子：
39.3
通讯作者：
Behar, Shlomo
中科院分区：
文献类型：
--
作者：
Mandelzweig, Lori;Battler, Alex;Behar, Shlomo
目的 我们的研究旨在检查欧洲和地中海盆地急性冠脉综合征 (ACS) 的治疗情况，并将对指南的遵守情况与 4 年前首次欧洲心脏病调查 (EHS-ACS-I) 中报告的指南进行比较。 方法和结果 在 2004 年进行的一项前瞻性调查 (EHS-ACS-II) 中，数据描述了急性冠状动脉综合征 (ACS) 的特征、治疗和结果 收集了 32 个国家 190 个医疗中心的 6385 名诊断为 ACS 的患者。 47% 的患者最初诊断为 ST 段抬高的 ACS，48% 的患者最初诊断为无 ST 段抬高，5% 的患者心电图模式未确定。 2000 年和 2004 年收集的数据比较显示相似的基线特征，但在 EHS-ACS-II 中更多地使用推荐药物和冠状动脉干预措施。在 ST 段抬高的患者中，初次再灌注的使用率略有增加（从 56% 增加到 64%），显着从纤溶治疗转向初次经皮冠状动脉介入治疗 (PPCI)。在接受初次再灌注治疗的患者中，PPCI 的使用率从 37% 上升至 59%。对参与两项调查的 34 个中心的数据分析显示，在推荐的药物治疗、干预措施和结果的使用方面有更大的改善。 结论 EHS-ACS-II 的数据表明，与 EHS-ACS-I 相比，对 ACS 治疗指南的依从性有所提高。
Aims Our study aimed to examine the management of acute coronary syndromes (ACS) in Europe and the Mediterranean basin, and to compare adherence to guidelines with that reported in the first Euro Heart Survey on ACS (EHS-ACS-I), 4 years earlier.Methods and results In a prospective survey conducted in 2004 (EHS-ACS-II), data describing the characteristics, treatment, and outcome of 6385 patients diagnosed with ACS in 190 medical centres in 32 countries were collected. ACS with ST-elevation was the initial diagnosis in 47% of patients, no ST-elevation in 48%, and undetermined electrocardiographic pattern in 5% of patients. Comparison of data collected in 2000 and 2004 showed similar baseline characteristics, but greater use of recommended medications and coronary interventions in EHS-ACS-II. Among patients with ST-elevation, the use of primary reperfusion increased slightly (from 56 to 64%), with a significant shift from fibrinolytic therapy to primary percutaneous coronary intervention (PPCI). The use of PPCI rose from 37 to 59% among those undergoing primary reperfusion therapy. Analysis of data in 34 centres that participated in both surveys showed even greater improvement with respect to the use of recommended medical therapy, interventions, and outcome.Conclusion Data from EHS-ACS-II suggest an increase in adherence to guidelines for treatment of ACS in comparison with EHS-ACS-I.