Bombesin-like peptides in rat brain: localization in synaptosomes and release from hypothalamic slices.
Bombesin-like peptides in rat brain: localization in synaptosomes and release from hypothalamic slices.
复制标题
大鼠大脑中的铃蟾肽样肽：定位于突触体并从下丘脑切片中释放。
DOI：
10.1016/0024-3205(80)90179-4
复制
发表时间：
1980
期刊：
影响因子：
6.1
通讯作者：
C. Pert
中科院分区：
文献类型：
--
作者：
T. Moody;N. Thoa;T. O'Donohue;C. Pert
研究了炸弹素样免疫反应在大鼠脑中的亚细胞分布。突触体中受体的数量明显多于线粒体部分，并且在突触体部分中bombesin样免疫反应的数量最大。此外，我们还研究了K+和veratridine刺激大鼠下丘脑片中bombesin样肽释放的免疫反应性，并以Ca++依赖的方式进行了研究。
The subcellular distribution of bombesin-like immunoreactivity in rat brain was investigated. The number of receptors was significantly greater in the synaptosomal than mitochondrial fraction and quantity of bombesin-like immunoreactivity was greatest in the synaptosomal fraction. Also, the release of bombesin-like peptides from rat hypothalamic slices was investigate K+and veratridine stimulated release of immunoreactivity in a Ca++-dependent manner.