Phytochemical investigation of Aglaia rubiginosa.
Phytochemical investigation of Aglaia rubiginosa.
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DOI：
10.1021/np9905923
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发表时间：
2000-04
影响因子：
5.1
通讯作者：
S. Weber;J. Puripattanavong;V. Brecht;A. Frahm
中科院分区：
文献类型：
--
作者：
S. Weber;J. Puripattanavong;V. Brecht;A. Frahm
对米仔兰（Aglaia rubiginosa）的甲醇叶提取物进行了植物化学研究，获得了15种类异戊二烯化合物，其中8种为新的天然成分。两种雄甾烷衍生物（1和2），以前合成的，也是通过微生物转化获得的;一种特殊的17-辛-环阿屯烷-环-A-开环酸（3）;四种环阿屯烷型三萜（4-7）;并分离出三种不寻常的胆固醇衍生物（8-10）沿着两种已知的达玛烷（11和12）、豆甾烷二醇（13）和β-谷甾醇及其β-D-葡糖苷。本文报道了新天然产物（1-3，6，7，8-10）的光谱结构鉴定。
The phytochemical investigation of a methanolic leaf extract of Aglaia rubiginosa furnished 15 isoprenoid constituents, eight of which represented new natural entities. Two androstane derivatives (1 and 2), previously synthesized, and also obtained by microbiological transformations; an extraordinary 17-octanor-cycloartane-ring-A-seco acid (3); four cycloartane-type triterpenes (4-7); and three unusual cholesterol derivatives (8-10) were isolated, along with two known dammaranes (11 and 12), a stigmastandiol (13), and beta-sitosterol and its beta-D-glucoside. Spectroscopic structure elucidation of the new natural products (1-3, 6, 7, 8-10) is described.