Distribution and fate of pancreatic enzymes in small intestine of the rat.
Distribution and fate of pancreatic enzymes in small intestine of the rat.
复制标题
大鼠小肠中胰酶的分布和命运。
DOI：
10.1152/ajplegacy.1962.202.2.285
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发表时间：
1962
期刊：
影响因子：
--
通讯作者：
M. Grossman
中科院分区：
文献类型：
--
作者：
D. Pelot;M. Grossman
测量大鼠小肠洗液的胰蛋白酶、胰凝乳蛋白酶和脂肪酶活性。胰液转移到体外导致酶从小肠迅速消失，16 小时后几乎完全消失。对于所有三种酶，小肠下半部的含量高于上半部。根据几个标准，灭活速率的顺序（从最慢到最快）是胰蛋白酶、胰凝乳蛋白酶和脂肪酶。完整大鼠的粪便中含有易于测量的所有这三种酶的量。
The trypsin, chymotrypsin, and lipase activities of washings of the small intestine of the rat were measured. Diversion of pancreatic juice to the exterior of the body resulted in rapid disappearance of enzymes from the small intestine with virtually complete absence after 16 hr. For all three enzymes, larger amounts were present in the lower than in the upper half of the small intestine. By several criteria the order of rate of inactivation, from least to most rapid, was trypsin, chymotrypsin, and lipase. Feces of intact rats contained readily measurable amounts of all three of these enzymes.